Cell therapies have been explored to treat patients with nervous diseases for over 20 years. Even though most kinds of cell therapies demonstrated neurorestorative effects in non-randomized clinical trials; the effects of the majority type cells could not be confirmed by randomized controlled trials. In this review, clinical therapeutic results of neurorestorative cell therapies according...Read More

Osteoarthritis (OA) was recently defined as an epidemic, and the lack of effective treatment is highly correlated to the limited knowledge regarding the underlying pathophysiology. Article by Johanna Bolander, Maria Teresita Moviglia Brandolina, Gary Poehling, Olivia Jochl, Emma Parsons, William Vaughan, Gustavo Moviglia, Anthony Atala.Read More

Spinal cord injury (SCI) is catastrophic damage for patients, their family, and society. Researchers and clinicians have been trying to find neurorestorative methods to recover their injured functions and structures. Cell therapy is one of the effective therapeutic strategies for SCI. And it can partially restore their neurological functions, which are once thought as permanent...Read More

By Hongyun Huang, Ziad M. Al Zoubi, Gustavo Moviglia, Hari Shanker Sharma, Anna Sarnowska, Paul R. Sanberg, Lin Chen, Qun Xue, Dario Siniscalco, Shiqing Feng, Hooshang Saberi, Xiaoling Guo, Mengzhou Xue, Milan R. Dimitrijevic, Russell J. Andrews, Gengsheng Mao, Robert Chunhua Zhao, Fabin Han.Read More

BACKGROUND: Glioblastoma multiforme (Gbm), the most aggressive glioma, presents with a rapid evolution and relapse within the first year, which is attributed to the persistence of tumor stem cells (tSc) and the escape of immune surveillance.Read More

Doctoral thesis of Dr. Gustavo A. Moviglia to obtain his degree of Doctor of Medicine, submitted to the Maimonides University in Buenos Aires.Read More

Ozone as Modulator of Resorption and Inflammatory Response in Extruded Nucleus Pulposus Herniation. Revising Concepts Ozone therapy has been used to treat disc herniation for more than four decades. There are several papers describing results and mechanism of action. However, it is very important to define the characteristics of extruded disc herniation. Although ozone therapy...Read More

By Huang, Young, Skaper, Chene, Moviglia et al. Published in the Journal of Orthopaedic Translation. Volume 20, January 2020, Pages 14-24Read More

Ozone therapy with local cellular immune modulation and disc progenitor cell implant is safe, effective and efficientRead More

The results presented here suggest that the combination of immune and regenerative cell therapy may play an important therapeutic role in clinical and histological recovery of chronic muscular atrophy.Read More