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Predifferentiated mesenchymal stem cells are cartilage producers and are combined with activated lymphocytes that facilitate repair. This treatment aims to provide cells that can differentiate into cartilage and bone, control the inflammatory process to stop the damage and generate an environment conducive to the repair of the compromised tissue.
The patient’s stem cells are extracted from abdominal subcutaneous fat, and inflammatory cells are obtained by peripheral blood collection. In a laboratory that meets the conditions for cell culture and differentiation, both stem cells are stimulated to differentiate into cartilage and effector lymphocytes are stimulated to provide the substances necessary to repair the tissue.
The cells are applied directly into the joint space using radioscopic or ultrasound guidance.
Clinical experience has shown that within the first month of receiving the implant 90% of patients experience a significant decrease in pain and improvement in joint functionality. Between 3 and 6 months changes are observed with respect to articular cartilage repair, which can be seen in MRI images and radiological studies.
In all the cases mentioned above, the implanted material comes from the patient’s own body, thus avoiding complications such as rejection and overgrowth. And because they are obtained from renewable sources, they can be applied as many times as necessary until the desired objective is achieved.
Osteoarthritis occurs when the cartilage at the ends of bones gradually wears away.
Osteoarthrosis is a high frequency pathology, where the main symptom is joint pain that compromises the normal movement of the joints. In advanced cases, bone deformities and loss of joint axes can also be seen.
It is produced as a result of an inflammatory process sustained over time that causes progressive damage and subsequent loss of articular cartilage. History of joint trauma, overweight, neuromuscular diseases, genetic predisposition are considered risk factors to suffer from this disease at younger ages and with more severe symptoms.
Epidemiological studies show that at the age of 60 years approximately 10% of the male population and 13% of the female population have some degree of involvement of this joint. At 70 years of age the prevalence of this pathology can reach 40% of the population.
The diagnosis of this pathology is made from the clinical picture and is complemented with images such as X-rays and MRI.
The symptomatology of osteoarthrosis is very clear. It is a painful disease, which limits the functionality of the affected joint and, until very recently, was considered incurable, due to the impossibility of regenerating or replacing the cartilage tissue. Other signs of the disease are joint sound, the appearance of deformities, inflammation and swelling of the affected joint.
It is worth mentioning that cartilage is a resistant but very flexible tissue that functions as a shock absorber between bones. It is also a very particular tissue because it does not contain blood vessels, so its irrigation is done from the bone, for which it is of utmost importance that it is properly adhered to it.